Protein Details: Chloride channel CLIC-like protein 1

Protein ID

ICDB_Pro_1423

Protein Name

Chloride channel CLIC-like protein 1

Gene Name

Clcc1

Organism

Mus musculus (Mouse)

Length

539 amino acids

AlphaFoldDB

AF-Q99LI2-F1-model_v4.pdb

Function

Seems to act as a chloride ion channel (By similarity). Plays a role in retina development .

Sequence

MLCRLLLCECLLLITGYAHDDDWIDPTDMLNYDAASGTMRKSQVRSGTSEKKEVSPDSSEAEELSDCLHRLDSLTHKVDSCEKKKMKDYESQSNPVFRRYLNKILIEAGKLGLPDENKVEMRYDAEILLSRQTLLEIQKFLSGEEWKPGALDDALSDILINFKCHDSEAWKWQFEDYFGVDPYNVFMVLLCLLCLVVLVATELWTYVRWYTQMKRIFIISFLLSLAWNWIYLYKMAFAQHQANIAGMEPFDNLCAKKMDWTGSLWEWFTSSWTYKDDPCQKYYELLIVNPIWLVPPTKALAITFTNFVTEPLKHIGKGAGEFIKALMKEIPVLLQIPVLAILALAVLSFCYGAGRSVPMLRHFGGPDREPPRALEPDDRRRQKGLDYRLHGGAGDADFSYRGPAGSIEQGPYDKMHASKRDALRQRFHSGNKSPEVLRAFDLPDTEAQEHPEVVPSHKSPIMNTNLETGELPGESTPTEYSQSAKDVSGQVPSAGKSSPTVDKAQLKTDSECSPPGGCPPSKEAAVAAHGTEPVSSPCG

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1126/science.1112014; 10.1371/journal.pbio.1000112; 10.1101/gr.2596504; 10.1073/pnas.0609836104; 10.1016/j.immuni.2008.11.006; 10.1016/j.cell.2010.12.001; 10.1371/journal.pgen.1007504

RefSeq

NP_001171242.1; NP_663518.1; XP_006501479.1; XP_017175050.1